Miso Clinic · Clinical Reference

XERF: a monopolar radiofrequency platform, and what is actually known about it

XERF is a monopolar radiofrequency device made by Lutronic, a Korean manufacturer. Its distinguishing design feature is that it runs two frequencies, 6.78 MHz and 2 MHz, rather than one. The most useful part of this page, though, is not the specification list. It is the section on evidence — because we could find no published clinical trial data for XERF itself, and the research we can cite belongs to monopolar radiofrequency as a category, not to this machine. This page keeps that distinction visible rather than blurring it.

Clinical reference About a 9-minute read Reviewed 2026 Miso Clinic, Daegu · Dr. Lee Chi-Hak 한국어판

In one paragraph

XERF is a monopolar radiofrequency (RF) lifting device manufactured by Lutronic Corporation in Goyang, Gyeonggi Province, South Korea. It passes a radiofrequency current through the skin to generate heat in the dermis and the layers beneath it. That heat contracts existing collagen fibres and triggers a wound-healing response that lays down new collagen over the following weeks. XERF combines two frequencies — 6.78 MHz and 2 MHz — with four handpieces of differing contact area, so that different regions of the face can be treated differently. Where injectable treatments work on the material inside the dermis, a device like this works on the structure below it.

At a glance

XERF
CategoryNon-invasive radiofrequency lifting device
ModeMonopolar RF
Frequencies6.78 MHz · 2 MHz
HandpiecesFour (XERF i05, i10; EFFECTOR E40, E60)
ManufacturerLutronic Corporation, Goyang, South Korea
Regulatory statusApproved as a medical device by Korea's MFDS — we could not find a published approval number
Approved device classGeneral-purpose electrosurgical unit
AnaesthesiaUsually none; topical anaesthetic where needed
DowntimeMost patients return to normal activity the same day
TargetsSkin laxity, softening jawline and cheeks, skin texture
Does not treatVolume loss, advanced laxity, pigmentary conditions
Published trialsNone found for XERF itself

What radiofrequency actually does to skin

Radiofrequency is not light. A laser works by being absorbed — by pigment, by water, by haemoglobin — and destroying a chosen target. RF instead pushes an alternating electrical current through tissue; charged molecules reverse direction with the current, and the friction produces heat. Because nothing is absorbing light, the constraints skin colour places on laser treatment apply much less here.

The heat is the whole point. Once tissue reaches a particular temperature range, collagen fibres partially unwind and contract immediately — what some patients feel as tightness on the day. Separately, the thermal insult switches on a repair response, and over the following weeks fibroblasts deposit new collagen. This is why radiofrequency treatments are assessed at two to three months, not on the day.

Monopolar and bipolar RF differ in where that heat ends up. In a bipolar device the current travels between two closely spaced electrodes, so energy stays relatively superficial. In a monopolar device the current leaves the handpiece, passes through the body and returns through a separate electrode placed elsewhere, travelling through a larger and deeper volume of tissue. Devices built for lifting are generally monopolar for that reason.

One caution before going further — the physics above is well established and applies to radiofrequency generally. "This mechanism is established" and "this device produces this result" are entirely different claims, and the second requires its own evidence. The evidence section below returns to that distinction.

Injections and devices work on different layers

A question that comes up in almost every consultation is whether to have a skin booster or a lifting treatment, as though the two were alternatives. They are not really competing, because they address different layers. Injectable boosters place material into the dermis or alter how it behaves, targeting density and texture. Radiofrequency puts heat into the deeper structural layer and targets a contour that has begun to descend. So a patient whose skin is thin but whose contour is intact will be disappointed by lifting alone, and the reverse holds too.

Injections work on the material in the dermis and devices work on the structure below it — which means the useful question is not which is better, but whether the two can be planned together. Our comparison of six collagen and skin boosters covers the injectable side; our other RF platforms are documented under Density and Oligio Kiss.

How XERF is configured — two frequencies, four handpieces

XERF does not use a single frequency. It operates at 6.78 MHz and at 2 MHz. In radiofrequency generally, frequency influences how current distributes through tissue: lower frequencies tend to spread more deeply, higher frequencies tend to concentrate energy more superficially. The manufacturer describes the combination of these two frequencies as addressing three tiers of depth — superficial, intermediate and deep.

Where that description comes from — the three-tier depth account above is the manufacturer's own, and within the limits of our search we found no independent verification of it. Actual heat distribution depends not only on frequency but on power setting, contact time, cooling and individual tissue impedance, so converting a specification-sheet frequency into millimetres of depth is not sound. We record the manufacturer's description as the manufacturer's description.

The four handpieces differ in contact area and maximum shot count. In practice the deciding question is whether a given tip can sit flat against a given part of the face. A large tip on a narrow, curved area makes poor contact; a small tip dragged across a broad cheek takes longer and delivers energy less evenly.

XERF handpieces
HandpieceContact areaMax shotsTypical use
XERF i055 × 10 mm400Narrow, thin areas
XERF i1010 × 10 mm300Small, contoured areas
EFFECTOR E4020 × 20 mm600General full-face use
EFFECTOR E6020 × 30 mm600Broad, thicker areas

These figures are the manufacturer's published specifications. How many shots a given treatment uses depends on the area covered and the condition of the skin; a higher shot count is not in itself a better treatment.

Who this suits, and who it does not

Reasonable candidates

  • Early to moderate laxity — a jawline losing definition, cheeks that sit lower than they did
  • Patients who do not want surgery and cannot afford visible downtime
  • Patients wanting firmness and texture addressed in the same session
  • Patients uncomfortable with needle-based treatments
  • Patients already treating the dermis with injectables whose contour has not changed

Where XERF alone will not get you there

  • Hollow cheeks or temples — radiofrequency creates no volume
  • Advanced laxity with actual folding of skin — that is surgical territory
  • Thin, depleted dermis — injectables that supply material come first
  • Melasma, redness or pore concerns as the principal complaint
  • An implanted electronic device — pacemaker, implantable defibrillator — in which case RF is contraindicated as a rule
  • Pregnancy, or active infection or broken skin at the treatment site
  • Metal implants or substantial filler in the treatment area — tell us beforehand

How good is the evidence

This is the section that matters most, so it is set out in three parts.

1. Evidence for XERF specifically

Within the limits of our search, we found no published clinical trial results generated using XERF. That statement means what it says and no more: not that the device does not work, but that we cannot verify performance from published data. A great many aesthetic devices sold in Korea are in the same position. Being common does not make it something to leave out of a clinical reference.

2. The regulatory facts

XERF is approved as a medical device by Korea's Ministry of Food and Drug Safety (MFDS). Two points need stating precisely.

First, we could not find a published approval number. The number the manufacturer publishes is an advertising pre-review number — "General-purpose electrosurgical unit combination-2024-16-054", valid to 22 April 2027. An advertising review number is not an approval number. Korea requires medical advertising to be pre-screened; that screening examines the wording of the advertisement, while device approval examines the safety and performance of the device itself. Presenting the former as though it were the latter is not accurate.

Second, as that number shows, the approved device class is "general-purpose electrosurgical unit." The product is sold as a lifting device, but its regulatory category is a broad one covering equipment that delivers RF energy to tissue. It is not an individual finding about facial lifting. Patients should know that before choosing.

3. Evidence for monopolar radiofrequency as a class

There is published research on monopolar radiofrequency generally. It was not conducted with XERF, and its findings should not be transferred to XERF as though they were. We cite it here with that attribution made explicit.

Cosmetics 2024;11(3):71 reported on 20 healthy women (mean age 47.95±6.02, Fitzpatrick skin types III–IV, mild to moderate facial laxity) assessed at 4, 12 and 24 weeks after a single monopolar RF treatment. Reported findings:

  • Statistically significant improvement in the jawline and nasolabial folds at 12 weeks (p<0.05)
  • Increased cheek elasticity from week 4 (p<0.01), sustained to 24 weeks
  • Mean pain during treatment of 0.4 out of 10
  • No burns or scarring reported

Read alone, those are encouraging numbers. They should be read alongside the limitations the authors state themselves:

  • No randomised control group — this was a prospective, evaluator-blinded cohort study
  • Twenty participants, all female — too small and too narrow to generalise from
  • No comparison against other anti-ageing technologies — so it supports no claim of superiority over anything

Put together: monopolar radiofrequency as an approach has small but consistent supporting evidence, and XERF as an individual device has no published evidence we could locate. We use XERF not because it is "clinically proven" — it would be untrue to say so — but because the mechanism of the class is well established and the range of handpiece sizes is genuinely useful across different regions of a face. We have no grounds to claim more.

On comparisons with other devicesno study has compared XERF directly against Density, Oligio Kiss, or any of the better-known RF or ultrasound platforms. This page therefore ranks nothing. If you meet material declaring one device superior to another, it is worth asking what evidence that ranking rests on.

What the appointment involves

The consultation starts by identifying which layer the visible change belongs to. If laxity dominates, radiofrequency is appropriate; if the dermis is thin and the texture poor, injectables come first. Both often apply, in which case we sequence them rather than combining everything into one visit.

Because RF passes current through the body, some history must be established before treatment. Please tell us about implanted electronic devices (pacemaker, defibrillator), metal implants, any filler or thread placement in the area, pregnancy, and skin disease. This is not a formality.

The session itself: the face is cleansed of makeup and oil, and a return electrode pad is placed so the current has a path back. Gel is applied to aid conduction and cooling, treatment zones are marked, and the handpieces are worked through in order — smaller tips for narrow regions, larger for broad ones. A full face takes roughly 40 minutes to an hour including preparation.

Power is not set to maximum at the start. We begin low and adjust against the heat you report feeling. If something feels hot rather than warm, say so immediately — that feedback is what the power setting is calibrated against.

Timeline

  1. Same day
    Redness and warmthTreated areas look flushed and feel warm. Some patients notice tightness — that is immediate collagen contraction, and it is not the final result.
  2. Day 1–3
    Mostly settledErythema usually clears within hours to a day; any swelling or pressure marks resolve within a few days.
  3. Week 2–4
    The ambiguous stretchImmediate tightening has faded and new collagen is not yet substantial. It is too early to conclude the treatment did nothing.
  4. Month 2–3
    Assessment pointRemodelling has accumulated. We compare against pre-treatment photographs and discuss what, if anything, comes next.
  5. Beyond
    ObservationWe have no data supporting a specific duration figure, so any repeat is decided on what we observe. Ageing continues; treatment does not freeze a point in time.

Pain, downtime and adverse effects

Pain — the usual sensation is repeated warmth building to brief moments of heat. The class study cited above reported mean intra-procedural pain of 0.4/10, but that figure belongs to that study's conditions; what you feel depends heavily on power settings and individual sensitivity. Areas close to bone — forehead, jawline, temples — tend to register more sharply.

Downtime — most patients return to normal activity the same day. Redness immediately afterwards may not be fully concealable with makeup, so allow some margin if you have something important that evening.

For the first few days

  • Cleanse gently with lukewarm water; do not rub the treated skin
  • Avoid sauna, jjimjilbang, strenuous exercise and alcohol on the day
  • Moisturise well and use sun protection diligently
  • Postpone exfoliants and actives for several days
  • Return to the clinic promptly if you notice unusual sensation or persistent pain
Adverse effects — erythema, swelling, a sensation of heat and temporary pressure marks are common after radiofrequency treatment and usually settle within hours to days. Less commonly, burns, blistering, post-inflammatory pigmentation, persistent pain or numbness, altered sensation, and localised fat atrophy causing a depression have been reported. If any of these appear, or if symptoms persist or worsen, return to the treating clinic for assessment. Radiofrequency is contraindicated as a rule in patients with implanted electronic devices such as pacemakers or defibrillators. Tell your clinician before treatment if you are pregnant, have infection, broken skin or metal implants at the treatment site, or have an uncontrolled systemic condition. The nature and severity of adverse effects vary with individual constitution, skin condition and the power settings used.

Common questions

Has XERF been shown to work in a clinical trial?
Within the limits of our search, no published clinical trial results for XERF itself could be found. What we can cite is research on monopolar radiofrequency as a class, and even that consists of small studies without control groups. So we cannot describe XERF as a clinically proven device. The mechanism behind the class is well established, but evidence for a class and evidence for an individual device are different things, and it is better not to merge them.
Is it an approved device? What is the approval number?
XERF is approved as a medical device by Korea's MFDS, but we could not find a published approval number. What the manufacturer publishes is an advertising pre-review number — "General-purpose electrosurgical unit combination-2024-16-054", valid to 22 April 2027 — and an advertising review number is not an approval number. Advertising review examines the wording of an advertisement; device approval examines the device. The approved device class is also worth knowing: "general-purpose electrosurgical unit", a broad category for equipment delivering RF energy to tissue.
Does using 6.78 MHz and 2 MHz together reach deeper?
The manufacturer describes the combination as addressing superficial, intermediate and deep tiers. We found no independent verification of that description. How deeply heat actually forms depends on power, contact time, cooling and individual tissue impedance as much as on frequency, so converting a specification-sheet frequency into a depth in millimetres is not a sound reading.
How many sessions, and how long does it last?
No standard protocol for XERF has been established by research, so we will not put a number on sessions or duration. The class study cited here followed patients for 24 weeks after a single treatment; beyond that we have nothing to cite. We review the actual change at two to three months and decide together about anything further. We do not sell multi-session packages up front.
Does it hurt? Will I need anaesthetic?
The usual experience is repeated warmth with brief hot moments. Most treatments are done without anaesthetic; topical anaesthetic is available if you are sensitive to pain. It is worth knowing, though, that fully numbing the skin and then raising the power is not a safe way to work — the sensation of heat is an important signal for setting the power. Tell us during the session rather than enduring it.
Can it be done over areas with filler or threads?
Tell us beforehand without fail. How heat interacts with an implanted material varies with the material, the amount and how long ago it was placed, and published guidance is thinner than one would like. We take the history, then separate the treatment zones, reduce the power, or postpone if the picture is unclear. The same applies to metal implants.
Should I do injectables or radiofrequency first?
They work on different layers. Injectables address the material and metabolism of the dermis; radiofrequency addresses the structure beneath it. If what bothers you is a descending contour, radiofrequency comes first; if it is skin that looks thin and depleted, injectables come first. Where both apply we space them out rather than doing everything in one visit. The six-booster comparison covers the injectable options.
What does it cost?
It depends on the areas treated, which handpieces are used and how many shots, and whether other treatments are combined. Korean medical advertising rules govern how treatment fees may be published, so we do not list them here; we will give you exact figures at consultation.

About the authoring clinic

This reference was written and reviewed by Dr. Lee Chi-Hak, director of Miso Clinic in Daegu, South Korea. Alongside XERF the clinic operates two other radiofrequency platforms — Density and Oligio Kiss — and separately stocks six collagen and skin boosters that work on the dermis. Holding several devices is not a claim that any one is superior; it is that a clinic with a single device ends up using it on every face. Our other references are collected in the Miso Clinic reference library.

Miso Clinic
DirectorDr. Lee Chi-Hak
Address4F Bombom Building, 125 Dongdeok-ro, Jung-gu, Daegu, South Korea · Exit 1, Kyungpook National University Hospital Station
Telephone+82 53-428-2700
KakaoTalkMiso Clinic channel
HoursWeekdays 11:00–19:00 (lunch 13:00–14:00) / Saturday 10:00–16:00 (no lunch break) / Closed Sundays and public holidays
Websiteclinicmiso.co.kr
Reference libraryMiso Clinic reference library
한국어세르프 진료 자료 (Korean)

References

  1. Suh D·H et al. Efficacy and Safety of Monopolar Radiofrequency for Tightening the Skin of Aged Faces. Cosmetics 2024;11(3):71. Twenty healthy women (mean age 47.95±6.02, Fitzpatrick III–IV) assessed at 4, 12 and 24 weeks after a single treatment. A prospective, evaluator-blinded cohort study without a randomised control group; the authors state as limitations the absence of randomised controls, the small all-female sample, and the lack of comparison with other anti-ageing technologies. Not a study of XERF — evidence for monopolar radiofrequency as a class.
  2. XERF product information, Lutronic Corporation. Source for the frequency configuration, handpiece specifications, and the manufacturer's account of treatment depth.
  3. Korean medical device advertising pre-review marking — "General-purpose electrosurgical unit combination-2024-16-054", valid to 22 April 2027. A pre-review of advertising wording; not an approval number.
  4. General literature on radiofrequency tissue heating and thermal collagen contraction — current paths in monopolar versus bipolar configurations, thermally induced changes in collagen structure, and subsequent neocollagenesis.
  5. Miso Clinic protocol — pre-treatment contraindication screening, handpiece selection by region, power titration, and informed-consent procedure.

This page provides general information about an aesthetic treatment and does not substitute for medical diagnosis or care. Outcomes and adverse effects vary with individual skin condition, age and underlying illness, and no result is guaranteed. Decisions about treatment should be made in an in-person consultation with a qualified clinician.

← Miso Clinic home