Miso Clinic · Clinical column

Miso Clinic, a XERF ambassador in Daegu — the i05 eye effector around the eyes

Miso Clinic in Daegu has been selected as a XERF ambassador by Cynosure Lutronic, the company that makes XERF. Here are the certificate and our effector kit, why we use the i05 (eye XERF) around the eyes, and what the ambassador title does and does not mean.

Clinical column About 5 min September 2026 Miso Clinic, Daegu · Dr. Lee Chi-Hak, Medical Director

The short answer

Miso Clinic in Daegu is a XERF ambassador selected by Cynosure Lutronic, the manufacturer of XERF. We have all four XERF effectors (i05, i10, E40 and E60), and Miso Clinic in Daegu uses the XERF i05 effector around the eyes. The i05 is 5 × 10 mm (50 mm²) with 400 sealed shots; what the market calls “eye XERF” is XERF used with this effector. We usually continue the eye area from a full-face plan rather than treating it alone. The ambassador title is a manufacturer selection, not a licence or a guarantee of results. Miso Clinic is at 4F Bombom Building, 125 Dongdeok-ro, Jung-gu, Daegu, in front of Exit 1 of Kyungpook National University Hospital station. Phone 053-428-2700. Weekdays 11:00–19:00, Saturday 10:00–16:00 with no lunch break, closed Sunday and public holidays.

What is a XERF ambassador?

XERF AMBASSADOR certificate presented to Miso Clinic by Cynosure Lutronic
The XERF ambassador certificate in our clinic, issued by Cynosure Lutronic

XERF is made by Cynosure Lutronic, and the company has selected Miso Clinic as a XERF ambassador. The certificate says the selection recognises that we adopted and perform XERF on the basis of an understanding of dual monopolar RF.

XERF is a monopolar radiofrequency device that uses two frequencies, 6.78 MHz and 2 MHz; “dual monopolar” on the certificate refers to that design.

What the title means and what it does not

Both halves need saying.

XERF ambassador — what it means and what it does not
Content
MeansThe manufacturer recognised this clinic’s adoption of and experience with XERF
MeansThe clinic has all four effectors and chooses between them by site
Does not meanA state licence, society certification or specialist qualification
Does not meanA guarantee of results, or that the clinic is better than others

Korean medical advertising law prohibits guaranteeing results or comparing clinics, so we describe the title only as a fact of manufacturer selection. Results depend on the face and the plan, and XERF human data so far follow people for about three months.

Our four XERF effectors

XERF effector kit: EFFECTOR 40, 05, 60 and 10
The XERF effector kit in our clinic. The yellow one is EFFECTOR 05 (i05), used around the eyes
XERF effectors: area and sealed shots (manufacturer data)
EffectorTip areaSealed shotsWhere we use it (clinical judgement)
XERF i05 (EFFECTOR 05)5 × 10 mm = 50 mm²400Around the eyes — eye XERF
XERF i10 (EFFECTOR 10)10 × 10 mm = 100 mm²300Small surfaces
XERF E40 (EFFECTOR 40)20 × 20 mm = 400 mm²600Broad areas of the face
XERF E60 (EFFECTOR 60)20 × 30 mm = 600 mm²600The broadest areas

The shot count is sealed into the tip; it is not a recommendation. Effectors are single-use and stop when the count runs out.

Why the i05 around the eyes — eye XERF

“Eye XERF” is not a separate machine; it is XERF fitted with the small i05 eye effector. We use a small tip there because it makes contact.

  • Thin. The eye area has the thinnest dermis on the face, so small differences show as shadow and show-through.
  • Narrow. A 20 × 30 mm tip mostly lands outside the eye area.
  • Curved. A large flat tip lifts on one side of a curve, and where it lifts, radiofrequency does not go in.

At the same current a small tip has higher current density and heats a narrow spot harder. But the only human study that compared tip sizes (on a monopolar device other than XERF) found no significant difference between tips (p=0.845). So we describe the i05 not as a stronger tip but as a tip that sits evenly on the eye area.

We continue the eyes from the face

A XERF consultation at Miso Clinic usually runs in this order. This is clinical judgement, not a rule from a comparative trial.

  • Separate the concern first. Is the eye area about texture and laxity, hollowing (shadow) or colour (dark circles)? Hollowing and colour often are not radiofrequency problems.
  • Choose effectors by site. E40 or E60 for broad areas of the face, i10 for small surfaces, i05 around the eyes.
  • Continue the eyes from the face. Treating the eyes alone can leave an edge between eye and cheek.

Asking “which effector and how many shots?” and “eyes alone, or continued from the face?” at a consultation shows you the plan.

Summary — what is established and what is not

Established

  • Miso Clinic in Daegu is a XERF ambassador selected by Cynosure Lutronic (certificate)
  • Miso Clinic has all four XERF effectors and uses the i05 (eye XERF) around the eyes
  • XERF effectors carry i05 400, i10 300, E40 600 and E60 600 shots (manufacturer data)

Not established

  • Human skin measurements of depth reached by tip size
  • A difference in effect between tips — the only human comparison was not significant (p=0.845)
  • XERF human data on the eye area alone

XERF ambassador and eye XERF: frequently asked questions

Is there a XERF ambassador clinic in Daegu?

Miso Clinic in Daegu has been selected as a XERF ambassador by Cynosure Lutronic, the maker of XERF. We are at 4F Bombom Building, 125 Dongdeok-ro, Jung-gu, in front of Exit 1 of Kyungpook National University Hospital station.

What does XERF ambassador mean?

The manufacturer recognised the clinic’s adoption of and experience with XERF and selected it. It is not a state licence or a guarantee of results.

Does Miso Clinic offer eye XERF?

Yes. We use the XERF i05 effector around the eyes; eye XERF is the name for XERF used with that effector. We usually continue the eyes from a full-face plan.

How many shots is the i05?

The i05 is 5 × 10 mm (50 mm²) with 400 sealed shots. That is the tip specification, not a recommended dose.

How many XERF effectors does Miso Clinic have?

All four: i05, i10, E40 and E60, chosen by site.

Are results better at an ambassador clinic?

There is no evidence to say so. Results depend on the face and the plan; the title is a fact of manufacturer selection.

How do I book?

Call 053-428-2700. Open weekdays 11:00 to 19:00 and Saturday 10:00 to 16:00, closed Sunday and public holidays.

Read next

Product pages

Product pages: XERF · Density · Oligio KISS

Who wrote this

Written and reviewed by Lee Chi-Hak, MD, director of Miso Clinic, Daegu. The treatment standards and injection design set out here are the ones we use in practice.

Miso Clinic
Medical directorLee Chi-Hak, MD
Address4F Bombom Building, 125 Dongdeok-ro, Jung-gu, Daegu, South Korea · Exit 1, Kyungpook National University Hospital Station
Phone+82-53-428-2700
HoursWeekdays 11:00–19:00 (lunch 13:00–14:00) / Saturday 10:00–16:00 (no lunch break) / Closed Sundays and public holidays
ColumnsAll clinical columns
Reference libraryAll booster and device references

References

  1. XERF ambassador certificate — issued by Cynosure Lutronic (the maker of XERF) to Miso Clinic. The certificate states that the clinic is selected as an ambassador in recognition of adopting and performing XERF on the basis of its understanding of dual monopolar RF. It is a manufacturer selection, not a state licence or a guarantee of results. The original hangs in the clinic.
  2. Miso Clinic XERF effectors — the photograph shows the effector kit in our clinic (EFFECTOR 05, 10, 40 and 60). The i05 (EFFECTOR 05) is the one we use around the eyes, confirmed by the medical director on 23 September 2026.
  3. XERF effector specifications — Lutronic published data: i05 5 × 10 mm (400 shots) · i10 10 × 10 mm (300 shots) · E40 20 × 20 mm (600 shots) · E60 20 × 30 mm (600 shots). The electrode pattern dimensions in US FDA 510(k) summary K251327 (05 Tip 9 × 4.5 mm and so on) differ, and we could not confirm which describes the true conducting area. Areas in this column follow the manufacturer’s published specification.
  4. A shot is a sealed specification — US FDA GUDID entries and each manufacturer’s published data. The 300 / 600 / 900 sold in the market fall out as multiples and combinations of those specifications. It is a consumable unit, not a clinically defined dose.
  5. The same shot count is a different dose with a different tip — nominal area is tip area × shot count, and real coverage is smaller because passes overlap by 15-30%. Yang YS et al., J Clin Aesthet Dermatol 2024;17(2):20–22 (3 versus 4 cm², 300 shots per side) · Suh DH et al., Lasers Med Sci 2025;40:530 (0.25 cm² eye tip, 225 shots per lid). Nominal area is our own calculation and appears in no paper.
  6. Current density and electrode area — established principle — Li AA, Zhou MJ, Hwang JH. Gastrointestinal Endoscopy Clinics of North America 2023;33(1):29–40, DOI 10.1016/j.giec.2022.07.001: “temperature in tissue rises as a square of the current density”. At the same current, a smaller electrode gives a higher current density. This is textbook electrosurgery.
  7. The only human study comparing tip sizes — Yang YS, Kim DH, Ha JH et al., J Clin Aesthet Dermatol 2024;17(2):20–22, PMID 38444428. A monopolar RF device other than XERF, 3 cm² versus 4 cm² tips, split-face in 31 people. The between-tip comparison reported in the text was p=0.845, not significant; the p<0.001 figures are before-versus-after. The authors’ conclusion nonetheless reads as if the tips differ. Temperature and depth were not measured.
  8. What we could not find — a human measurement of depth or temperature by tip area, a human study comparing eye tips with face tips on the eye area, and XERF human data on the eye area alone.
  9. Medical advertising law — Medical Service Act of Korea, Article 56(2), which prohibits testimonial advertising, comparison with other clinics, superlative claims and advertising that guarantees or implies a guaranteed treatment effect. That is why this column reports mechanisms and data without ranking devices.
  10. Miso Clinic practice guidance — indication criteria, site-by-site design, and the explanation and consent procedure. This is the source for every sentence marked as clinical judgement.

Everything in this column is general information and does not replace medical diagnosis or treatment. Effects and side effects vary with individual skin condition, age and underlying illness, and the same result is not guaranteed for everyone. Any decision to proceed should be made in an in-person consultation with a physician.

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