Miso Clinic · Clinical column

Eight things to tell your doctor before an injectable treatment

There is a set of questions we ask at consultation. Without an explanation they sound like paperwork — but these eight are the ones where your answer genuinely changes whether, or when, we treat. Here is what to mention, and why each one matters.

Clinical column About an 8-minute read August 2026 Miso Clinic, Daegu · Dr. Lee Chi-Hak 한국어 칼럼

The short answer

Eight things should always be mentioned before an injectable treatment: (1) every medication you take, especially blood thinners; (2) previous fillers and boosters; (3) a recent infection, or an upcoming vaccination or dental appointment; (4) pregnancy or breastfeeding; (5) allergies and past reactions to treatment; (6) a history of cold sores; (7) any isotretinoin use; (8) an upcoming CT or MRI scan. Some of these move the appointment; others mean a prescription is needed first.

Why this comes first

Medical history in aesthetic practice is often treated as a formality — a hurdle before the booking, from the clinic’s side, and an odd interrogation over “just an injection” from the patient’s.

But putting material into a face is among the harder things to undo. Of the seven boosters we use, only BYRYZN — a cross-linked hyaluronic acid — can be dissolved. The other six have to be waited out.

So this is part of the treatment, not a preamble to it. Each of the eight below is here because the answer changes the plan.

1. Your medications — blood thinners above all

Aspirin, antiplatelet drugs and anticoagulants mean the same treatment bruises far more, and for longer. Supplements such as ginkgo, omega-3 and vitamin E push in the same direction, more mildly.

The most important point: do not stop them on your own. These are usually prescribed for cardiac or vascular disease, and stopping without medical advice carries a risk that is not remotely comparable to a bruise.

What we do instead is one of three things: keep the medication and design around the areas that bruise most, ask you to raise it with your prescribing doctor, or move the date if you have something important coming up.

Saying it is easy. “I take aspirin daily, for my heart” is enough — you do not need the exact name. A photograph of the packet or prescription is the most reliable option.

2. Previous fillers and boosters — what, where, when

This is the one most often left out. Sometimes it was years ago and genuinely forgotten; more often it was done elsewhere and feels awkward to raise.

But what is already in the tissue determines what can go in next. Where a material that cannot be dissolved is already present — CaHA (Radiesse, DCLASSY) or PCL (GOURI) — both volume and depth have to be planned differently.

You do not need the product name. Roughly when, roughly where, and whether it was an injection or a thread already changes the assessment considerably.

It can feel uncomfortable to mention. Some patients hesitate to talk about treatment they had at another clinic. We are not asking in order to judge it. We ask because we need to know what is in that tissue now to treat it safely today.

3. A recent infection, or an upcoming vaccination or dental appointment

Almost nobody expects this one to be relevant.

Hyaluronic acid filler sites have been reported to swell and harden weeks to months after an uneventful treatment. This is called a delayed inflammatory reaction, and reported triggers include systemic infection, vaccination, local trauma and dental procedures. The treatment goes well; then a bout of flu or a scale-and-polish months later is followed by swelling at the site.

Reported incidence ranges widely by product, from 0.02% to 4.25%. Uncommon — but if you do not know it exists, you look for the cause in the wrong place.

So we ask two things: are you unwell now (if so, we wait until it settles), and is a vaccination or dental appointment coming up. The second usually does not mean no treatment — it means leaving a gap so that cause and effect stay legible.

4. Pregnancy and breastfeeding

There is essentially no research on aesthetic injectables in pregnancy or breastfeeding. We advise against them not because there is evidence of harm, but because there is no evidence of safety.

Tell us if you are planning a pregnancy too. It changes the scheduling more than the decision itself.

5. Allergies and past reactions

Three questions:

  • Reactions to local anaesthetic — light-headedness or palpitations after dental anaesthesia, for instance. Many boosters contain lidocaine
  • Reactions to previous fillers or boosters — unusually prolonged swelling, or a nodule
  • Any autoimmune diagnosis — the data here is thin, so we proceed carefully

People often skip these as “probably nothing”. A reaction that happened once can happen again, and it is the kind of thing that changes which product and which anaesthetic we use.

6. Whether you get cold sores

Herpes simplex lies dormant and reactivates when provoked. Injecting around the mouth can be that provocation.

Told in advance, we can prescribe an antiviral prophylactically. Once a lesion has appeared, we wait for it to settle.

7. Isotretinoin

The acne medication. For years the rule of thumb was “no procedures for six months after stopping”.

That rule has been re-examined. A 2017 systematic review and expert consensus in JAMA Dermatology reviewed 1,485 procedures across 32 papers and concluded there was insufficient evidence to delay superficial chemical peels, manual dermabrasion, cutaneous surgery, laser hair removal and fractional laser procedures. It still advised against mechanical dermabrasion and fully ablative laser.

That is not the same as “anything goes”. It depends on the procedure, and that review did not cover injectables at all. So we ask whether and when you took it, and judge against the treatment in question.

8. An upcoming CT or MRI

CaHA products (Radiesse, DCLASSY) are radiopaque — they appear white on CT. A radiologist who does not know they are there may read them as a lesion or a foreign body.

We check for planned imaging beforehand, and afterwards we ask you to mention the treatment whenever you have a scan. This is not a danger; it is information that prevents unnecessary further investigation.

What you do not need to worry about saying

  • Treatment at another clinic — we are not asking to judge it
  • “It didn’t work” — this is among the most useful things you can tell us. It helps identify what did not fit
  • Budget — choosing the one treatment that helps most now beats stretching to do everything. Doing less is also a plan
  • “I haven’t decided yet” — a consultation on its own is a perfectly good outcome

Afterwards — when to call immediately

Call us straight away. Severe pain during injection, skin turning white or dusky, or any change in vision. These are rare but can signal a vascular complication, where time determines the outcome.
Also worth being seen, even days later. Redness, swelling or heat; pain that is increasing rather than settling; or the treated area swelling suddenly weeks or months later (the delayed inflammatory reaction described above). Coming in at the time is far simpler than describing it afterwards.

In short

You do not need to memorise all eight. In practice this covers it:

  • Your medications — a photo of the packet
  • Anything previously put into your face — even just roughly when and where
  • Being unwell, or having a medical or dental appointment coming up

We will ask about the rest. And when in doubt, say it. If it turns out to be irrelevant we simply move on; proceeding without something that mattered is much harder to undo.

Frequently asked questions

I don't know the exact name of my medication.
A photograph of the packet or prescription is the most reliable option. If that is not possible, 'something for my heart' or 'a blood pressure tablet' is enough to work from — we can identify the class. The only genuinely unhelpful outcome is not mentioning it at all because you could not name it.
How many days before should I stop taking aspirin?
Do not stop it on your own. These medications are usually prescribed for cardiac or vascular disease, and the risk of stopping without advice is far greater than a bruise. Whether to pause it, and from when, is a decision for the doctor who prescribed it. Our first approach is to keep you on it and design around the areas that bruise, or to move the date.
Do I need to mention filler I had years ago at another clinic?
Yes, always. Materials that cannot be dissolved, such as CaHA and PCL, alter the tissue at that site for years. You do not need the product name — roughly when, roughly where, and whether it was an injection or a thread already changes how much we place and how deep. We are not asking in order to judge the previous treatment.
I have a flu vaccination next week. Can I still be treated?
Usually yes. But delayed inflammatory reactions at hyaluronic acid filler sites have been reported following vaccination and infection, so leaving a gap between the two makes it far easier to identify the cause if anything does happen. We look at both dates together at consultation.
I am trying to conceive. Is treatment possible?
We advise against it, because there is essentially no research in pregnancy or breastfeeding — not because harm has been shown, but because safety has not. If you are planning a pregnancy, tell us; it changes the scheduling more than the decision.
I get cold sores often. Is that relevant?
Yes. Herpes simplex lies dormant and reactivates when provoked, and injecting around the mouth can be that provocation. Told in advance, we can prescribe an antiviral prophylactically. If a lesion is already present, we wait for it to settle.
I took isotretinoin. Do I have to wait six months?
That was the long-standing rule, but it has been re-examined. A 2017 systematic review in JAMA Dermatology found insufficient evidence to delay superficial chemical peels, manual dermabrasion, cutaneous surgery, laser hair removal and fractional laser, while still advising against mechanical dermabrasion and fully ablative laser. That review did not cover injectables, so it is not a blanket clearance. Tell us whether and when you took it and we will judge against the specific treatment.
I have a CT scan coming up. Should I mention the treatment?
If you have had a CaHA product such as Radiesse or DCLASSY, yes. CaHA is radiopaque and appears white on CT, and a radiologist who does not know it is there may read it as a lesion or foreign body. This is not dangerous — it simply prevents unnecessary further investigation. Hyaluronic acid and the other classes are not affected.

Who wrote this

Written and reviewed by Lee Chi-Hak, MD, medical director of Miso Clinic in Daegu, South Korea. The clinic keeps seven collagen and skin boosters with genuinely different mechanisms alongside three lifting devices, and selects among them according to what kind of ageing the face is actually showing. Our approach is restraint: choosing to do less is also a clinical decision.

Miso Clinic
Medical directorLee Chi-Hak, MD
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References

  1. Spring LK, Krakowski AC, Alam M, et al. Isotretinoin and Timing of Procedural Interventions: A Systematic Review With Consensus Recommendations. JAMA Dermatol. 2017 — a systematic review and expert consensus covering 1,485 procedures across 32 papers. It found insufficient evidence to delay superficial chemical peels, manual dermabrasion, cutaneous surgery, laser hair removal and fractional laser, while continuing to advise against mechanical dermabrasion and fully ablative laser. It did not examine injectables, so it is cited here only as evidence that the old rule has been re-examined, not as the basis for any decision.
  2. Litaiem N, et al. Delayed inflammatory reaction to hyaluronic acid filler following COVID-19 vaccination: A case report and review of the literature. J Cutan Aesthet Surg. doi:10.25259/JCAS_31_2024 — the source for the reported triggers of delayed inflammatory reactions (systemic infection, vaccination, local trauma, dental procedures) and the 0.02–4.25% incidence range. It is a case report with a literature review, and the width of that incidence range is itself the limitation of the figure.
Deliberately absent. A specific number of days to stop an anticoagulant, antiviral doses and durations, risk estimates by autoimmune condition — these depend on the individual, and stating them as a rule would be worse than useless. This column is about what to mention; the judgement that follows belongs in the consultation.

This column provides general information and does not replace medical diagnosis or treatment. Results and side effects vary with skin condition, age and underlying health, and no outcome is guaranteed. Do not stop any prescribed medication on your own — speak to the doctor who prescribed it.

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