Miso Clinic · Clinical column

How do XERF and a collagen booster go together?

"It is saggy and hollow at the same time." One tool is not enough. XERF and collagen boosters work on different things and are often planned together.

Clinical column About 5 min November 2026 Miso Clinic, Daegu · Dr. Lee Chi-Hak, Medical Director

The short answer

XERF handles sagging by depth; collagen boosters such as Juvelook, Gouri or Sculptra rebuild thin skin and broad hollows over months. Two concerns, two tools. I have not found a trial showing the combination beats either alone. Miso Clinic in Daegu performs XERF often and frequently recommends this pairing.

Each does a different job

XERF official model Park Shin-hye photo shoot, Miso Clinic Daegu
XERF and collagen boosters
HandlesWhen change shows
XERFSagging and firmness, by depthJudged at about 3 months
Collagen boosterThin skin and broad hollowsBuilds over 2–3 months

Order and timing

Sagging first means XERF first; base first means booster first. Same day or a few weeks apart. In 1,040 Korean patients given filler and radiofrequency together, no burns, filler migration or early loss were reported.

→ Read more: Results and sessions

Which booster?

Thin skin: Juvelook or Gouri; broad hollows: Sculptra or Juvelook Volume. Deep hollows get dissolvable hyaluronic acid filler first. Miso Clinic in Daegu performs XERF often and keeps all four effectors (i05, i10, E40, E60).

How does the consultation work, and how do I book?

On a first visit we take photos from the front, at 45 degrees and from the side, and together we pick the one concern that bothers you most. I'll ask about any medications you take, any metal or electronic implants in your face, and whether you might be pregnant, and then I split things into what we can do today and what can wait for later. It's completely fine to come in just for a consultation and go home.

How to reach Miso Clinic
ItemDetails
BookingNaver booking · KakaoTalk chat · Phone +82-53-428-2700
Location4F Bombom Building, 125 Dongdeok-ro, Jung-gu, Daegu (Exit 1, Kyungpook National University Hospital Station, Line 3)
HoursWeekdays 11:00–19:00 · Saturday 10:00–16:00, closed Sundays and public holidays

XERF with a collagen booster: FAQ

Same day?

Possible; order and areas are set after examination.

Do I need both?

If there is one concern, one tool. Nothing extra.

When do we judge?

Both change over 2–3 months, so then.

Where can I get a XERF consultation in Daegu?

At Miso Clinic in Daegu (4F Bombom Building, 125 Dongdeok-ro, Jung-gu, Exit 1 of Kyungpook National University Hospital Station). Book through Naver booking, KakaoTalk or by phone at +82-53-428-2700. Weekdays 11:00–19:00, Saturday 10:00–16:00, closed Sundays and public holidays.

Read next

Product pages

Related: XERF · XERF series

Who wrote this

Written and reviewed by Lee Chi-Hak, MD, director of Miso Clinic, Daegu. The treatment standards and injection design set out here are the ones we use in practice.

Miso Clinic
Medical directorLee Chi-Hak, MD
Address4F Bombom Building, 125 Dongdeok-ro, Jung-gu, Daegu, South Korea · Exit 1, Kyungpook National University Hospital Station
Phone+82-53-428-2700
HoursWeekdays 11:00–19:00 (lunch 13:00–14:00) / Saturday 10:00–16:00 (no lunch break) / Closed Sundays and public holidays
ColumnsAll clinical columns
Reference libraryAll booster and device references

References

  1. XERF device information — Maker data from Cynosure Lutronic: monopolar radiofrequency at 6.78 MHz + 2 MHz ("dual monopolar"), ICD gas cooling, effectors i05 (5×10 mm, 400 shots), i10 (10×10 mm, 300), E40 (20×20 mm, 600), E60 (20×30 mm, 600). Korean device class: general electrosurgical unit; US FDA 510(k) K251327 (intended use: electrocoagulation and haemostasis).
  2. Heat distribution of the two frequencies — Ko 2025, computer model and pig tissue (most authors from the maker): 2 MHz heats broadly and deeper in fat, 6.78 MHz locally along fibrous septa. Not measured in human skin.
  3. Three human studies of XERF — Hwang 2025 (20 women, one session, 12 weeks, blinded raters picked the after photo 80% of the time), Weiss 2026 (39 people, two sessions, 92.3% rated improved at 90 days, maker-funded), Erlich 2026 (16 people, retrospective, one session, 3 months). None had a control group; follow-up at most about 3 months. Pain without anaesthesia averaged in the 4s out of 10.
  4. Genuine tip check — From the maker film "Find My XERF": (1) check the genuine sticker when the tip box is opened, (2) receive the membership card after treatment, (3) scan the QR code on the back of the card with your phone, (4) enter your details to complete the authentication.
  5. XERF at Miso Clinic — XERF Ambassador selected by the maker, small-tip (i05, i10) periorbital training completed, XERF Certified Clinic. All four effectors on site. No radiofrequency that day with facial metal or electronic implants, pregnancy or skin inflammation; results judged at around 3 months with matched photos. Maker certifications are not national qualifications or guarantees.
  6. Photos and films — The official model photos and brand films were provided by Cynosure Lutronic with permission for clinic promotion (2026-11-12). The Miso Clinic logo was added by the clinic.
  7. Korean medical advertising law — Medical Service Act Article 56(2): no testimonials, no comparisons with other clinics, no superlatives. That is why there are no prices, reviews or before-and-after photos here.

Everything in this column is general information and does not replace medical diagnosis or treatment. Effects and side effects vary with individual skin condition, age and underlying illness, and the same result is not guaranteed for everyone. Any decision to proceed should be made in an in-person consultation with a physician.

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